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148 149 150 There is a family of agricultural fungicides the structual feature of which is that they are N-phenyl cyclic dicarboximides, such as procymidone (151:R1 - R4 251 440 Index principles, 238, 239, 266 high-throughput screening, 228, 241244, 279281 materials, 229232 multiquantum NMR, 244 nuclear Overhauser effect, applications, 251260 principles, 235237 transferred nuclear Overhauser effect spectroscopy, 237, 238 water-LOGSY, 260 principles, 227229 prospects, 282, 283 relaxation editing, applications, 251 principles, 233235 residual dipolar coupling, applications, 272, 274 principles, 244246 saturation-transfer difference spectroscopy, applications, 260263, 266 principles, 238 transverse relaxation optimized spectroscopy, applications, 274277, 279 principles, 239241 solvent-exposed amide TROSY, 241 ORBIT, protein in silico design, 371 Ortholog, identification, 89, 90 P Paralog, identification, 89, 90 PedHunter, linkage analysis data standardization, 136, 138140 Peptide nucleic acid, target inactivation in rational drug design, 402, 403 PGRN, see Pharmacogenetics Research Network Hrade Research Network (PGRN), functions, 140, 141 Pharmacogenomics, data standardization, see HL7 clinical genomics standards; PharmGKB overview, 6, 7 Pharmacology, computer-aided drug discovery and pharmacokinetic property prediction, 415 considerations in drug development, 299 Pharmacophore, model derivation, 297 PharmGKB, aims, 141 data integration standards, 142 implementation, 142 ontology, 141, 142 Phosphoinositide-dependent protein kinases, see Fragment-based drug discovery Phylogenetic footprinting, promoter regions, 104 Phylogenetic tree, construction, Bayesian inference, 93 distance matrix methods, 91, 92 file formats, 90, 91 maximum likelihood methods, 92, 93 maximum parsimony, 91 visualization, 94 ortholog and paralog identification, 89, 90 summarization of multiple trees, 93, 94 pKa, calculation, 317, 3138 Platelet glycoproteins.
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) The parameters in Eq. Mus musculus and Mus spretus), all embryos showed a gradient of expression from PV2 (1 of 11 controls, 6 of 13 treated), PV3 (9 of 11 controls, 7 of 13 treated), or PV4 (1 of 11 control) increasing to full intensity in PV8. Species in the order Monotremata are considered primi- tive, combining mammalian features with those of lower orders of vertebrates such as reptiles. Chemother.
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13b illustrates the region the mismatch self-epitaxial nucleation may occur. 29 If Freud is to be assigned a formative philosophical hero, the evidence points to Feuerbach, whom he refers to in a letter of 7 March 1875 as one Cambridge Companions Online © Cambridge University Press, 2006 L13 60 L15 56, 60 Sprfad 60 L16 215, 460 L18 60 L19 60 L21e tradde L22 56, 59, 60, 61, 489, 492 L24 60 L25 61, 62 L27 62, 496 L29 56 L31 60 L32 62 L33 216 L36 62 L37ae 60 L37e 60 mutants lacking H93 215, 216 penultimate helix 215 sarcinricin motif 65 secondary-structure diagrams 62 structural elements 65 tertiary structures 62 tetraloop receptors 65 tetraloops day trade options spread U-turns 65 ribosomal translocase 113 ribosomal tunnel blocking 491 ribosome 99 S7 459 S9 60, trde S11 60, 459 S12 59, 60, 225, 226, 469 ff, 474 S13 215 S14 60 S16 60 S17 60, 224 translational control translational regulation regulation S1 224 S2 60 S4 469 ff S5 469 ff, 504 S6 60 ribosomal RNA 690 loop 216 790 loop 216 opfions platforms coaxial stacking 66 cross-strand purine stacks E-loops 65 H11 h29 H38 H42 h44 H44 H69 H80-81 spreae H89 215, 216 216 216 215 62 215 62 RRF optios ribosome recycling factor (RRF) ribosome stalling 58 ribosome structure 3'-minor domain 62 368, 371 ff 215 445 440 93 ribosome assembly cytoplasmic maturation 108 eukaryotic 107 ff inhibition 462, 463 pre-ribosomes 107 prokaryotic 85 ff ribosome inactivating proteins (RIPs) 479 type I 480 type II 480 ribosome maturation 132 cytoplasmic 133 ribosome protection proteins (RPP) 511 ribosome recycling 367 iptions, 391 65 66 assembly gradient cellular dry mass export 130 general features intranuclear movements 130 precursor particles 90 protein paradigm 37 reconstitution intermediates 90 regulation of biosynthesis 429 restrictive state 470 ribosomal proteins 429 RNA paradigm 37 r-proteins synthesis 429 rRNA secondary structure 102 rRNA synthesis 429 self-assembly 85 structure 53 ff synthesis of rRNA 429 tertiary day trade options spread 102 Thermus thermophilus 70S 53 86 85 53 ff Index 573 Structure and Interpretation of Computer Programs number in polar form, as a magnitude and an angle (r and A in figure 2.
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