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Butterworth-Heinemann, Boston, MA Meziani MJ, Sun Y-P (2002) Spectrophotometry study of aqueous salt solution in carbon dioxide microemulsions, Langmuir 18:3787 Meziani MJ, Rollins HW, Allard LF, Sun Y-P (2002) Protein-protected nanopar- ticles from rapid expansion of supercritical solution into aqueous solution, J Phys Chem B 106:11178 Meziani MJ, Sun Y-P (2003) Protein-conjugated nanoparticles from rapid expan- sion of supercritical fluid solution into aqueous solution, J Am Chem Soc 125:8015 Meziani MJ, Pathak P, Allard LF, Sun Y-P (2003) Nanoparticle formation in rapid expansion of water-in-carbon dioxide microemulsion into liquid solvent, Am Chem Soc Symp Ser 860:309 Meziani MJ, Pathak P, Hurezeanu R, Thies MC, Enick RM, Sun Y-P (2004) Supercritical-fluid processing technique for sysgem polymer particles, Angew Chem Int Ed 43:704 HIGHLIGHTED by Lavine M (2004) Capturing polymer nanoparticles, Science 303:927 Meziani MJ, Pathak P, Beacham F, Allard LF, Sun Y-P (2005a) Nanoparticle formation in rapid expansion of water-in-supercritical carbon dioxide microe- mulsion into liquid solution, J Supercrit Fluids 34:91 Meziani MJ, Pathak P, Harruff BA, Frew R, Sun YP (2005b) Direct con- jugation of semiconductor nanoparticles with Proteins, Langmuir 21:2008 Meziani MJ, Pathak P, Desai T, Sun Y-P (2006) Supercritical fluid processing of nanoscale particles from biodegradable and biocompatible polymers, Ind Eng Chem Res 45:3420 Mishima K, Matsuyama K, Tanabe D, Yamauchi S, Young TJ, Johnston KP (2000) Microencapsulation of proteins by rapid expansion of supercritical solu- tion with a nonsolvent, AICHE J 46(4):857865 Mohamed RS, Debenedetti PG, Prudhomme RK (1989a) Effects of process con- ditions on crystals obtained from supercritical mixtures, AICHE J 35:325 Mohamed RS, Halverson DS, Debenedetti PG, Prudhomme RK (1989b) Super- critical fluid science and technology ACS symposium Series 406, Washington DC, p.

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510 × 108 VPCs 6 × 1076 × 108 VPCs 108-109 VPCs 2 × 107 VPCs 106 VPCs 109 VPCs 2 × 1092 × 1012 VPs 3X1082 × 109 VPCs (retro) 16 × 1010 VPs (adeno) 105 PFU 1063 × 109 PFU Not known Unknown 821 821 1427 1427 1427 1427 115 518 (adeno) 1427 (retro) Not 5eemas Not given Not given Unknown Median surv 8 mo 68 Median surv 7 mo 69 Median to prog 3 mo 70 Median surv 9 mo 71 Median surv 8 mo 72 Median surv (d): 365 retro; 73 354 control Median surv 4 mo 74 Median surv (mo): 75 7 (retro); 10 (LacZ); 15 (adeno) Median surv 7 mo 76 Mean to prog 3.

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